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Disintequik MCC 25
Sheffied Tabletting System Disintequik MCC 25 is a co-processed excipient consisting of 75% Alpha monohydrate lactose and 25% Microcrystalline Cellulose (MCC). The processing results in a co-agglomeration compound of the two ingredients, spray dried lactose and MCC, preserving the identity of each component. Prior to processing, both ingredients meet all of the requirements as outlined in the current monographs of the EU, JP and NF. Disintequick MCC 25 reduces raw materials QC Testing, Manufacturing Steps and process validation. A Drug Master File is available. Added benefits include: reduction of blending issues, low dust generation, the avoidance of costly wet granulation processes, improved flowability and content uniformity during compression.
Pharmaceutical Ingredients
Mannogem Powder - Mannitol
Mannogem Mannitol Powder is an excellent tablet diluent/
filler for use in wet granulation and lyophilization. It dries
rapidly, resulting in shorter processing time and increased
productivity.
Mannitol is also a good excipient for hot melt extrusion
applications. It melts without decomposition at
a temperature of approximately 165° C. Its rapid
recrystallization upon cooling make it an attractive carrier to
improve solubility of poorly soluble APIs.
Pharmaceutical Ingredients
Mannogem EZ Spray Dried - Mannitol
The proprietary process used to manufacture Mannogem EZ Spray Dried - Mannitol yields a porous material with lower disintegration times, a narrow particle size distribution, enhanced flow, and compression properties. It is due to these properties that Mannogem EZ is excellent in ODT formulations. It produces tablets with higher hardness than other excipients at comparable compression forces, and its higher surface area allows Mannogem EZ to work well as a base for ordered mixing with micronized APIs and low dose formulations. Mannogem® Mannitol products are manufactured from sugar cane or from corn starch/syrup.
Pharmaceutical Ingredients
Mannogem XL - Mannitol
Mannogem® XL, an innovative approach to mannitol designed to improve the formulation experience and enhance formulation performance.
Pharmaceutical Ingredients
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