Pharmaceutical Ingredients

Rapamycin, also known as sirolimus , is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection and treat a rare lung disease called lymphangioleiomyomatosis. It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants.

Mycophenolate mofetil, also known as MMF or CellCept, is a prodrug of mycophenolic acid and classified as a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH). This drug is an immunosuppressant combined with drugs such as Cyclosporine and corticosteroids to prevent organ rejection after hepatic, renal and cardiac transplants.

Tacrolimus is an immunosuppressive drug. It is used after allogeneic organ transplant to lower the risk of organ rejection and also as a topical medication in the treatment of T-cell-mediated diseases such as eczema and psoriasis.

Everolimus is a medication used as an immunosuppressant to prevent rejection of organ transplants and in the treatment of renal cell cancer and other tumours. Much research has also been conducted on everolimus and other mTOR inhibitors as targeted therapy for use in a number of cancers.