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Magaldrate (Al5Mg10(OH)31(SO4)2,xH20) is a basic aluminium and magnesium compound possessing a layer structure connected by water and sulphate bridges. It is crystalline by nature. This unique crystal lattice structure results in its high reactivity. The antacid effectiveness of magaldrate can be used to treat peptic ulcers because it neutralizes gastric acid very quickly while buffering the pH (keeping it between 5 and 6) even in the presence of proteins and pepsin.

Simethicone is an orally administered antifoaming agent. It is mainly used to reduce gas from the gastrointestinal tract (GIT) in patients complaining from recurrent flatulence. Simethicone is a mixture of polydimethylsiloxane and hydrated silica gel.

Advantol® is a robust, off-the-shelf excipient system that allows the formulator fast product development. It requires no special manufacturing equipment or tooling. Simply add the active to Advantol, dry blend and compress.

Mannogem AG Granular Mannitol USP/EP has a larger particle size that has shown to contribute to a softer texture for chewable tablets.