QA SYNOVEA HR for brightening/even-toning. Multiple clinical studies demonstrated its strong performance in skin brightening/even toning and hyper-pigmentation control. Clinically proven to be four-times more effective than Hydroquinone. Works by modulating eight sites in the melanogenesis pathway;.Boosting E-cadherin; Combining HR with Niacinamide (Vitamin B3) provides very effective skin brightening & even toning to all skin colors. Anti-aging benefits is attributed to its collagen and elastin stimulatory activity.