A cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. It has been proposed for the treatment of asthma, rhinitis, skin allergies and anaphylaxis.

Loratadine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes and runny nose. Loratadine is used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching and other cold or allergy symptoms.

Carbamazepine is an anticonvulsant medication used primarily in the treatment of epilepsy and neuropathic pain. It is used in schizophrenia along with other medications and as a second-line agent in bipolar disorder.

Desloratadine is a tricyclic H₁ antagonist that is used to treat allergies. It is an active metabolite of loratadine.