Biopharma

IPTG is commonly used in cloning procedures that require induction of β-galactosidase activity.

PMSF is often used in lysis buffer to assist in preserving proteins of interest during protein isolation and sample preparation.

Tricine can be used in a wide array of biological applications including as a component in media formulations. Specific applications include buffers for electrophoresis, protein purification and diagnostic reagent production.

Guanidine hydrochloride has commonly been used for the isolation of RNA, to denature globular proteins and for protein refolding studies. It can also be used to facilitate the generation of tryptic peptides for analysis of complex protein samples.