Mannogem Mannitol Powder is an excellent tablet diluent/
filler for use in wet granulation and lyophilization. It dries
rapidly, resulting in shorter processing time and increased
productivity.
Mannitol is also a good excipient for hot melt extrusion
applications. It melts without decomposition at
a temperature of approximately 165° C. Its rapid
recrystallization upon cooling make it an attractive carrier to
improve solubility of poorly soluble APIs.
The proprietary process used to manufacture Mannogem EZ Spray Dried - Mannitol yields a porous material with lower disintegration times, a narrow particle size distribution, enhanced flow, and compression properties. It is due to these properties that Mannogem EZ is excellent in ODT formulations. It produces tablets with higher hardness than other excipients at comparable compression forces, and its higher surface area allows Mannogem EZ to work well as a base for ordered mixing with micronized APIs and low dose formulations. Mannogem® Mannitol products are manufactured from sugar cane or from corn starch/syrup.