Newaple is an extract from Artemisia Princeps Pams, a Korean natural medicine. It reduces the expression of inflammatory reactions reducing IL-31 and IL-33. It also reduces histamine, a neurotransmitter with a central role as a mediator of itching.

Portulaca is extracted from the whole plant of Purslane, which is known for its traditional Chinese medicine properties to treat burns, inflammation and itching. It calms down sensitive skin, because it reduces irritation and inflammation thanks to the release of IL-1. It also protects skin cells against UV.

Fructan is a polymer obtained by fermentation of sucrose. It consists of thousands of fructose types found in plants and microorganisms. It is a powerful moisturizer, because it can hold a lot of water compared to its weight. It prevents release of cytokines, which is responsible of skin inflammation.