Aqualon, a brand of sodium carboxymethylcellulose (CMC), has proven to be a popular ingredient in ophthalmic formulations due to its unique attributes. Sodium CMC is a water-soluble polymer derived from cellulose, with low viscosity and low molecular weight, and a degree of substitution of 0.7.
One of the key attributes of Aqualon CMC 7LF PH BET is its rheology. The polymer helps to maintain thixotropy of the system, including the solute and solvent throughout the process. This means that particles remain suspended, and the action of viscosity modification occurs at a fast rate and remains for a longer period of time. Additionally, the time required for solution/suspension is less if we follow the proper agitation process and temperature. This attribute makes Aqualon a valuable ingredient in ophthalmic formulations that require stability and uniformity.
Another attribute of Aqualon and Blanose is that they offer low endotoxin and low bioburden. This is particularly important in ophthalmic formulations, as the eyes are a sensitive area that is prone to infection.