Excipients

Mannogem Mannitol Powder is an excellent tablet diluent/ filler for use in wet granulation and lyophilization. It dries rapidly, resulting in shorter processing time and increased productivity. Mannitol is also a good excipient for hot melt extrusion applications. It melts without decomposition at a temperature of approximately 165° C. Its rapid recrystallization upon cooling make it an attractive carrier to improve solubility of poorly soluble APIs.

Pharmaburst 500 produces fast disintegrating tablets that are hard enough to withstand the mechanics of production, storage, transportation, and being pushed out of a blister pack, yet will disintegrate rapidly so the patient can swallow their medication comfortably.

Advantol® is a robust, off-the-shelf excipient system that allows the formulator fast product development. It requires no special manufacturing equipment or tooling. Simply add the active to Advantol, dry blend and compress.

Mannogem AG Granular Mannitol USP/EP has a larger particle size that has shown to contribute to a softer texture for chewable tablets.