Sheffied Tabletting System Disintequik MCC 25 is a co-processed excipient consisting of 75% Alpha monohydrate lactose and 25% Microcrystalline Cellulose (MCC). The processing results in a co-agglomeration compound of the two ingredients, spray dried lactose and MCC, preserving the identity of each component. Prior to processing, both ingredients meet all of the requirements as outlined in the current monographs of the EU, JP and NF. Disintequick MCC 25 reduces raw materials QC Testing, Manufacturing Steps and process validation. A Drug Master File is available. Added benefits include: reduction of blending issues, low dust generation, the avoidance of costly wet granulation processes, improved flowability and content uniformity during compression.

Advantol® is a robust, off-the-shelf excipient system that allows the formulator fast product development. It requires no special manufacturing equipment or tooling. Simply add the active to Advantol, dry blend and compress.

Mannogem AG Granular Mannitol USP/EP has a larger particle size that has shown to contribute to a softer texture for chewable tablets.

Mannogem Mannitol Powder is an excellent tablet diluent/ filler for use in wet granulation and lyophilization. It dries rapidly, resulting in shorter processing time and increased productivity. Mannitol is also a good excipient for hot melt extrusion applications. It melts without decomposition at a temperature of approximately 165° C. Its rapid recrystallization upon cooling make it an attractive carrier to improve solubility of poorly soluble APIs.